2021 PROSPECTS & POINTS
| MLB | PLAYER | POINTS | MWBL | 2021 | POS | AGE | ETA |
| TB | Franco, Wander | 100 | TIJ | SS | 19 | 2021 | |
| BAL | Rutschman, Adley | 99 | YSS | C | 22 | 2021 | |
| DET | Torkelson, Spencer | 98 | FRE | 3B/1B | 21 | 2022 | |
| SEA | Kelenic, Jarred | 97 | CRK | OF | 21 | 2021 | |
| SEA | Rodriguez, Julio | 96 | CHI | OF | 20 | 2022 | |
| SDP | Gore, MacKenzie | 95 | PIT | LHP | 21 | 2021 | |
| KC | Witt Jr., Bobby | 94 | DET | SS | 20 | 2022 | |
| SDP | Abrams, C.J. | 93 | SWD | SS | 20 | 2022 | |
| PIT | Hayes, Ke’Bryan | 92 | TIJ | 3B | 24 | 2021 | |
| TOR | Pearson, Nate | 91 | CRK | RHP | 24 | 2021 | |
| DET | Mize, Casey | 90 | CHI | RHP | 23 | 2021 | |
| ATL | Pache, Cristian | 89 | VAL | OF | 22 | 2021 | |
| STL | Carlson, Dylan | 88 | SEL | OF | 22 | 2021 | |
| CWS | Vaughn, Andrew | 87 | BET | 1B | 22 | 2021 | |
| MIA | Sanchez, Sixto | 86 | HIW | RHP | 22 | 2021 | |
| SFG | Luciano, Marco | 85 | CRK | SS | 19 | 2023 | |
| MIN | Lewis, Royce | 84 | CRK | SS | 21 | 2021 | |
| ATL | Anderson, Ian | 83 | SEL | RHP | 22 | 2021 | |
| TB | Patino, Luis | 82 | VIR | RHP | 21 | 2021 | |
| MIA | Bleday, J.J. | 81 | CRK | OF | 23 | 2021 | |
| DET | Greene, Riley | 80 | CHI | OF | 20 | 2022 | |
| TOR | Martin, Austin | 79 | JNE | SS/OF | 21 | 2022 | |
| SFG | Bart, Joey | 78 | FRE | C | 24 | 2021 | |
| DET | Skubal, Tarik | 77 | FRE | LHP | 24 | 2021 | |
| DET | Manning, Matt | 76 | SWD | RHP | 23 | 2021 | |
| MIN | Kirilloff, Alex | 75 | RRG | OF/1B | 23 | 2021 | |
| BAL | Rodriguez, Grayson | 74 | TIJ | RHP | 21 | 2022 | |
| MIA | Meyer, Max | 73 | TIJ | * | RHP | 21 | 2022 |
| KC | Lynch, Daniel | 72 | MSS | LHP | 24 | 2021 | |
| KC | Lacy, Asa | 71 | PIT | LHP | 21 | 2022 | |
| SEA | Hancock, Emerson | 70 | DAL | RHP | 21 | 2022 | |
| NYY | Dominguez, Jasson | 69 | TEM | OF | 17 | 2024 | |
| SEA | Gilbert, Logan | 68 | RRG | RHP | 23 | 2021 | |
| TB | Arozarena, Randy | 67 | RRG | OF | 25 | 2021 | |
| ATL | Waters, Drew | 66 | VAL | OF | 22 | 2021 | |
| CLE | Jones, Nolan | 65 | LBD | 3B | 22 | 2021 | |
| STL | Liberatore, Matthew | 64 | CRK | LHP | 21 | 2022 | |
| STL | Gorman, Nolan | 63 | FRE | 3B | 20 | 2022 | |
| CWS | Kopech, Michael | 62 | TCP | RHP | 24 | 2021 | |
| CWS | Madrigal, Nick | 61 | YSS | 2B | 23 | 2021 | |
| HOU | Whitley, Forrest | 60 | TIJ | RHP | 23 | 2021 | |
| PHI | Howard, Spencer | 59 | FRE | RHP | 24 | 2021 | |
| PIT | Gonzales, Nick | 58 | FRE | 2B | 21 | 2022 | |
| BOS | Casas, Triston | 57 | JNE | 1B | 21 | 2022 | |
| SDP | Campusano, Luis | 56 | CRK | C | 22 | 2021 | |
| TOR | Groshans, Jordan | 55 | SWD | SS | 21 | 2022 | |
| ARI | Carroll, Corbin | 54 | TIJ | OF | 20 | 2022 | |
| NYM | Alvarez, Francisco | 53 | CHI | C | 19 | 2023 | |
| BOS | Downs, Jeter | 52 | COL | SS/2B | 22 | 2021 | |
| TB | Brujan, Vidal | 51 | MSS | 2B/SS | 22 | 2021 | |
| CLE | McKenzie, Triston | 50 | VIR | RHP | 23 | 2021 | |
| PIT | Priester, Quinn | 49 | PIT | RHP | 20 | 2023 | |
| LAA | Marsh, Brandon | 48 | LBD | OF | 23 | 2021 | |
| COL | Veen, Zac | 47 | LBD | * | OF | 19 | 2024 |
| ARI | Robinson, Kristian | 46 | CRK | OF | 20 | 2022 | |
| CWS | Crochet, Garrett | 45 | YSS | LHP | 21 | 2021 | |
| LAD | Ruiz, Keibert | 44 | CHI | C | 22 | 2021 | |
| LAD | Gray, Josiah | 43 | CRK | RHP | 23 | 2021 | |
| CIN | Lodolo, Nick | 42 | VIR | LHP | 22 | 2021 | |
| CHC | Marquez, Brailyn | 41 | SBL | LHP | 22 | 2021 | |
| CHC | Davis, Brennen | 40 | HIW | OF | 21 | 2022 | |
| SDP | Hassell, Robert | 39 | SWD | * | OF | 19 | 2023 |
| TEX | Jung, Josh | 38 | CIN | 3B | 22 | 2021 | |
| PIT | Cruz, Oneil | 37 | MCM | SS | 22 | 2022 | |
| MIL | Mitchell, Garrett | 36 | PIT | OF | 22 | 2023 | |
| MIA | Chisholm, Jazz | 35 | CRK | SS/2B | 23 | 2021 | |
| NYM | Mauricio, Ronny | 34 | POR | SS | 19 | 2022 | |
| MIA | Cabrera, Edward | 33 | CCC | RHP | 22 | 2021 | |
| BAL | Kjerstad, Heston | 32 | BET | OF | 21 | 2023 | |
| BAL | Hall, D.L. | 31 | TIJ | LHP | 22 | 2022 | |
| CIN | Greene, Hunter | 30 | SEL | RHP | 21 | 2022 | |
| TB | McKay, Brendan | 29 | SBL | LHP | 25 | 2021 | |
| ATL | Langeliers, Shea | 28 | BET | C | 23 | 2022 | |
| LAA | Detmers, Reid | 27 | BET | LHP | 21 | 2022 | |
| NYM | Allan, Matthew | 26 | VIR | RHP | 19 | 2023 | |
| PHI | Abel, Mick | 25 | YSS | * | RHP | 19 | 2024 |
| BAL | Mountcastle, Ryan | 24 | CRK | OF/1B | 23 | 2021 | |
| TEX | Huff, Sam | 23 | MSS | C | 23 | 2021 | |
| ARI | Perdomo, Geraldo | 22 | CCC | SS | 21 | 2021 | |
| MIN | Larnach, Trevor | 21 | YSS | OF | 23 | 2021 | |
| ARI | Thomas, Alek | 20 | DAL | OF | 20 | 2022 | |
| SFG | Ramos, Heliot | 19 | VIR | OF | 21 | 2021 | |
| SFG | Bishop, Hunter | 18 | SEL | OF | 22 | 2023 | |
| TB | McClanahan, Shane | 17 | HOL | LHP | 23 | 2021 | |
| TB | Edwards, Xavier | 16 | HOL | 2B/SS | 21 | 2022 | |
| CIN | Hendrick, Austin | 15 | VAL | * | OF | 19 | 2024 |
| TOR | Woods-Richardson, Simeon | 14 | TIJ | RHP | 20 | 2021 | |
| NYY | Schmidt, Clarke | 13 | RRG | RHP | 24 | 2021 | |
| CHC | Amaya, Miguel | 12 | TCP | C | 21 | 2021 | |
| TB | Baz, Shane | 11 | VIR | RHP | 21 | 2022 | |
| TEX | Dunning, Dane | 10 | CCC | * | RHP | 26 | 2021 |
| SEA | Kirby, George | 9 | SBL | RHP | 23 | 2021 | |
| BOS | Dalbec, Bobby | 8 | CRK | 3B/1B | 25 | 2021 | |
| NYM | Baty, Brett | 7 | JNE | 3B | 21 | 2022 | |
| CIN | Stephenson, Tyler | 6 | JNE | C | 24 | 2021 | |
| MIL | Turang, Brice | 5 | MCM | SS/2B | 21 | 2022 | |
| MIN | Balazovic, Jordan | 4 | VAL | RHP | 22 | 2022 | |
| CLE | Freeman, Tyler | 3 | LBD | SS | 21 | 2022 | |
| WAS | Cavalli, Cade | 2 | MCM | * | RHP | 22 | 2022 |
| SEA | Trammell, Taylor | 1 | TIJ | OF | 23 | 2021 |